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Oleander Extract for Cancer Successfully Passes Phase I FDA Trial

by Tony Isaacs

A recently concluded FDA phase 1 human toxicity trial of a concentrated oleander extract has found that it can safely be administered in large doses and that it apparently can be effective against a wide variety of cancers. The results of the trial were presented at this year's American Society of Clinical Oncology (ASCO) which was held June 3-7 at Memphis, Tennessee.

The primary purpose of the trial was to determine maximum safe dosage levels. Even so, 7 of the 46 trial participants had their cancers stabilized for 4 or more months despite the fact that far less than maximum doses were administered for the majority of the trial. The stabilized cancers included bladder, colorectal, fallopian tube, breast, appendecal and pancreatic carcinomas.

In the trial, patients were given increasing doses of oral oleander extract in cycles where the drug was administered for 21 out of 28 days in each cycle. Dosage began at 0.6 mg per day and was slowly increased until a maximum safe dose level of 10.2 mg per day was determined, as indicated in the conclusion of the trials abstract:

"Conclusions: PBI-05204 is well tolerated up to 10.2/mg/day with very little AEs (adverse events) or cardiotoxicity."

http://www.asco.org/ASCOv2/Meetings/Abstracts?&vmview=abst_detail_view&confID=102&abstractID=80984

The oleander extract tested was developed by Phoenix Biotech and used a liquid carbon dioxide extraction method. A previous phase I trial of an injected aqueous oleander extract never did reach a maximum safe level. Instead the trial was halted when the amount injected became too large to practically exceed. It has since been determined that the aqueous extract can also be administered safely and effectively orally.

The next step in the FDA trial process would be a larger scale multi-location phase II trial. Such a trial will depend on large amounts of funding, perhaps hundreds of millions of dollars. Even if funding is found, it could take years before the new drug goes through the entire trial process and is available for cancer patients.

The good news for cancer patients is that oleander extract is already available in supplemental form, including several versions developed by Naturopathic PhD Marc Swanepoel which are made by a pharmaceutical manufacturing company in South Africa. In addition, a home version of oleander extract can be safely made at home for only pennies. See:

http://www.tbyil.com/oleandersoup.htm

http://www.tbyil.com/tips.htm

Note: The oleander plant is very toxic in raw form. Anyone who decides to make a homemade oleander extract should exercise caution in handling raw plant material and should not deviate at all from the proven instructions. The instructions are based upon the oleander extract developed by noted Turkish doctor H. Z. Ozel, who has used oleander extract successfully in thousands of patients for over 40 years. It was Dr. Ozelís extract which was tested in the previous phase I FDA trial.

Success rates for supplemental oleander over the past five years have been reported to be 85% for stage III and IV cancers and 95% for stage I and II cancer patients when combined with healthy changes in diet, nutrition, lifestyle and other healthy cancer fighting and immune boosting supplements. One example of a highly successful protocol which includes oleander and other natural items is:

http://www.tbyil.com/anticancer.htm

Besides cancer, oleander extracts have been found to be very effective against HIV/AIDS, hepatitis-C and other immune disorders. In one double blind placebo controlled trial conducted at a South Africa AIDS clinic, one of Dr. Swanepoel's oleander extracts was found to be 100% effective in reversing HIV symptoms and low white blood cell counts.

http://www.tbyil.com/HIV_Clinical_Trial.htm

To find out more about the medicinal history and uses of oleander, see:

http://www.tbyil.com/oleander1.htm

http://www.tbyil.com/oleander2.htm

http://www.tbyil.com/oleander3.htm

http://www.tbyil.com/oleander4.htm

http://www.tbyil.com/autophagy.htm

http://www.tbyil.com/Oleander_Case_Reports_Studies.htm

http://www.tbyil.com/Mysteries_Oleander.htm

http://www.tbyil.com/Africa-Oleander-HIV.htm

http://curezone.com/forums/fm.asp?i=1661043#i

Other sources included:

http://www.freepatentsonline.com/7402325.html
http://www.clinicaltrials.gov/ct2/show/study/NCT00554268?term=PBI-05204&rank=1&show_desc=Y#desc
http://curezone.com/forums/fm.asp?i=1795312#i

About the author

Tony Isaacs is a natural health advocate and researcher and the author of books and articles about natural health including "Cancer's Natural Enemy".  Mr. Isaacs articles are featured at Natural News, the Health Science Institute's Healthiertalk website, the Crusador online, AlignLife, the Cancer Tutor, the American Chronicle and several other venues. Mr. Isaacs also has The Best Years in Life website for baby boomers and others wishing to avoid prescription drugs and mainstream managed illness and live longer, healthier and happier lives naturally. In addition, he hosts the Yahoo Oleandersoup Health group of over 3500 members and the CureZone"Ask Tony Isaacs - Featuring Luella May" forum.

 

    

Your hosts Tony Isaacs and Luella May

Click here to visit our CureZone Health Forum: Ask Tony Isaacs: Featuring Luella May Ė Natural Health, Cancer, Longevity and Home & Herbal Remedies.

  

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