Share

Home  Article Directory  Healthy Recipes  Natural Remedies  Beating/Avoiding Cancer  Natural Living  Anti-Aging/Longevity  Pets/Animals   Diets/Weight Loss   Humor  Inspiration  The TBYIL Complete Supplement & Health Catalog  Contact Us

 

Oleander Induces Autophagic Cell Death in Pancreatic Cancer Cells

Part 5 of the Oleander Article Series

by Tony M. Isaacs
author of
Cancer’s Natural Enemy

(The Best Years in Life) In a study published in peer reviewed journals, an aqueous extract of the oleander plant was found to induce and increase autophagy in pancreatic cancer cells.  Autophagy is a process in which a cell destroys proteins and other substances in its cytoplasm (the fluid inside the cell membrane but outside the nucleus), which may lead to cell death, as happened in the study with pancreatic cancer cells.  The study was led by noted MD Anderson researcher Doctor Robert Newman, the lead research scientist in a number of important studies on oleander and oleander compounds. The study appears to provide yet another important piece of evidence in understanding why oleander has proven to be successful against a great many forms of cancer, especially pancreatic cancer. Oleander has had notable success against pancreatic cancer, which is one of the most difficult cancers to conquer.

Details of the study can be found by clicking this link:

Autophagic_Cell_Death.pdf

In previous studies, oleander extracts have been shown to 1) inhibit angiogenesis, the process where cancer produces blood vessels and spreads, 2) inhibit the NF-kB factor in cancer cells, which is the process that cells use to protect themselves when they come under attack, 3) induce apoptosis, or normal cell death, in cancer cells, and 4) greatly stimulate immune activity.

Oleander has had success against a broad spectrum of cancers since Doctor H. Ziya Ozel began working with oleander extracts in 1966 in Turkey.  Dr. Ozel subsequently went on to successfully treat thousands of patients, many of whom were in advanced stages and whom mainstream chemo and radiation treatments had failed to help.  The Salud Integral Clinic has continued that success for the past several years and also reports successes against a wide variety of cancers and other cell proliferative diseases and immune disorders.

For several years, Phoenix Biotech was the only active manufacturer of the patented oleander medication Anvirzel, which has passed FDA phase I toxicity trials and has been used successfully outside the United States for many years, including the Salud Integral Clinic in Honduras, which Phoenix Biotech owns.  Phoenix has spun off the Anvirzel portion of it's operations, including the Honduras facility, and is now concentrating all of it's efforts in oleander medicine on a new pill form and proprietary extraction method that uses liquid carbon dioxide and micro-fine particles of oleander and which is reported to result in a greater concentration of the cardiac glycosides and no loss of all the supporting compounds.

The spin off unit is named Nerium Biotechnology in Canada, whose president is former Phoenix manager Dennis Knocke.  In a conversation with Mr. Knocke, he reported that pancreatic cancer is one of the greatest areas of success for Anvirzel.  Although Anvirzel is very successful against virtually all cancers, very few other options have much success at all against the deadly and fast growing pancreatic cancer.

Pancreatic cancer, which is normally fatal within only a few months of diagnoses, yet Mr. Knocke reports that they have pancreatic cancer patients still alive years later who are healthy and doing well.  He also reported speaking with two of the newer pancreatic cancer patients recently and said that both of whom were alive and doing well five months after their diagnosis.  One patient's cancer had stopped growing and was stabilized and another had no signs of tumors or cancer at all now.

Other examples of Anvirzel's successes with difficult cancer include, melanoma, esophageal cancer and brain tumors.  Oleander, which crosses the blood/brain barrier has been very successful against brain tumors in general and childhood brain tumors in particular.

How Oleander Extract Works Against Cancer

An extract of oleander (Nerium oleander) that contains oleandrin is effacious in the treatment of tumors. This use is species-specific and is correlated with Na, K-ATPase isoforms. Additionally, oleandrin raises the intracellular calcium level, releases cytochrome C from mitochondria, and induces apoptosis through a caspase-dependent pathway.

Also, oleandrin inhibits the release of tumor growth factor bFGF from tumors. bFGF has many tumor-proliferating effects including promoting angiogenesis.

Oleandrin was determined to block the activation of NF-kB, which in turn blocks the cell-survival function of NF-kB. In addition, a non-water-soluble fraction of oleander is able to produce oxygen free-radicals in tumor cells, which may contribute to tumor cell injury and death. Oleandrin, particularly when in the context of oleandrin and oleander extract, is able to cross the blood-brain-barrier.

Evidence suggests that oleandrin and oleander extract have antiviral activity. Development continues as the oleander extract is nontoxic to normal cells and exhibits multiple antitumor activities such as inducing apoptosis, reducing molecular mechanisms of cell survival, and inhibiting tumor-promoting factor bFGF-2.

Image and Description Source: Salud Integral http://www.saludintegral.hn/

Records of the medicinal use of oleander date back at least 3500 years. The Mesopotamians in the 15th century BC believed in the healing properties of oleander and the ancient Babylonians used a mixture of oleander and licorice to treat hangovers. Roman soldiers also regularly took an oleander extract for hangovers. Pliny, the Elder of ancient Greece, wrote about the appearance and properties of oleander. Arab physicians first used oleander as a cancer treatment in the 8th century AD.

Today, the most common forms of oleander are Anvirzel, a dietary supplement from South Africa known as Sutherlandia OPC (http://www.tbyil.com/SOPC_Orders.htm), the recently introduced OPC Plus (made by the same pharmaceutical manufacturing company as Sutherlandia OPC but shipped from the U.S.), and an increasingly popular home remedy known as "oleander soup" which is based on the original patent by Dr. Ozel.

Excerpted from the author's book "Cancer's Natural Enemy".

Be sure to read the entire Oleander Series of articles:

The Oleander Article Series

See also:

The Best Years in Life's Comprehensive and Highly Effective Natural Anti-Cancer Protocol

The Best Years in Life Cancer Alternatives Resource Page

Tony Isaacs is a natural health advocate and researcher and the author of books and articles about natural health including Cancer's Natural Enemy.  Mr. Isaacs articles are featured at The Truth About Cancer, the Health Science Institute's Healthiertalk website, CureZone, the Crusador online, The New Zealand Journal of Natural Health, the Cancer Tutor and several other venues. Mr. Isaacs also has The Best Years in Life website for baby boomers and others wishing to avoid prescription drugs and mainstream managed illness and live longer, healthier and happier lives naturally. In addition, he hosts the Yahoo Oleandersoup Health group of over 3500 members and the CureZone Ask Tony Isaacs- Featuring Luella May forum

Sutherlandia OPC Oleander Based Supplements

To see the latest items on sale at Utopia Silver. click on the above link, or click HERE

See more natural health articles Here.

To find out more or to order, click the above image or click HERE.

Be sure to visit our sponsors:

 

Be Sure to Visit our Sponsors and Friends:

JOIN THRIVE MARKET - GOOD FOR YOU AND YOUR WALLET
Join Us and Get Your Favorite Organic Foods & Non-GMO Brands Delivered to Your Door!

        

   

The Best Years in Life uses and highly recommends Malwarebytes

For the best in health information, subscribe to The Best Years in Life Newsletter featuring articles by Tony M. Isaacs

Sign Up Now

Click on the Yahoo Groups Image to Join The Oleandersoup Forum - Beating and Avoiding Cancer + Natural Health
 

Powered by health.groups.yahoo.com

If you would like to donate to help us keep this web site active and growing, click on the button above.   Much thanks! - Tony & Luella

 

Click here to visit our CureZone Health Forum: Ask Tony Isaacs: Featuring Luella May– Natural Health, Cancer, Longevity and Home & Herbal Remedies.

         

Misty*, My Buddy, Little Rascal & Lady the "found dogs" - Official Mascots of The Best Years in Life

*Rest in peace sweet girl - almost 17 years of wonderful memories.

Available Now!
Click here or on the image above for more information

The plant you need to make your own home remedy for cancer, hepatitis-C & more may be growing in your back yard!  Read all about this proven  remedy plus much more on how to naturally beat illness and live a longer, healthier and happier life.

Sutherlandia OPC

The ultimate immune booster and modulator from South Africa. Contains pure Nerium oleander plus Sutherlandia frutescens (the "South Africa Cancer Bush"). As featured in the book "Cancer's Natural Enemy"

NAC SUSTAIN

Combination Quick Release and Time Release format of N-Acetyl-L-Cysteine. Powerful antioxidant amino acid and a precursor to the critical antioxidant glutathione, which exerts protective effects on the body, including detoxification and intracellular defense against oxidative stress.

An essential complimentary supplement to use with Sutherlandia OPC.

  

Doctors Best High Absorption Turmeric/Curcumin

Doctor's Best Curcumin with Curcumin C3 Complex and BioPerine contains a potent standardized extract of Curcuma longa root, known as turmeric. Turmeric has centuries of tradition in Ayurvedic healing and has demonstrated potent antioxidant properties in scientific studies. Curcuminoids may benefit the joints, brain, heart and circulatory system by helping to neutralize free radicals. Be sure to use Discount Code XOT949 to get $5 or more off.

Cell Forte Purple Mushroom Defense 120 Veggie Caps

Cell Forté Purple Mushroom Defense, your first line of defense, supports proactive deep immune health naturally with efficacious levels of the four powerhouse mushrooms. In addition, antioxidant-rich Purple Kculli Corn provides the perfect growth medium, generating ultimate antioxidant and immune power. The exclusive Purple Power Blend:

*Is clinically proven to intensify natural killer (NK) cell activity
*Boosts the body's natural defenses against harmful free radicals
*Delivers More Than 3x's The Antioxidant Power Than the Leading Competitor!

Nerium OPC Skin Therapy Creme

Look years younger and heal and eliminate all kinds of skin problems. Nerium OPC Skin Therapy Creme is simply amazing - an “anti-aging” and “skin rejuvenating” creme for wrinkles, age/liver spots on the face, neck, and hands, as well as cells in a state of disordered morphology,

intraMAX

intraMAX™

100% Organic MicroComplexed™ IntraCELL™ Level IV Technology ~ 415 Nutrients All-In-One, Perfect Whole Foods & Phyto Nutrition ~ Super Energizing ~ All Natural Defense The Most Scientifically Advanced, Clinically Proven, Health Promoting Organic Nutritional Supplement Available Today!

The Best Colloidal Silver
on the Planet

Contains about 30 ppm of .9999 pure silver in de-ionized water.  Silver inhibits the growth of one-celled organisms, (such as bacteria and viruses) by deactivating the organism's oxygen metabolism enzymes. In turn, this destroys its' cell membranes, stopping the replication of its' DNA.

The Krill Miracle™

The Krill Miracle™

Concentrated Omega 3, 6 & 9, Many Times More Powerful than Fish Oil.

RM-10 Mushroom Immune Defense

Garden of Life's proprietary blend of 10 mushrooms , plus Cat's Claw and Potenzyme selenium. Use referral code XOT949  for $5 off your first order.

Liposomal Vitamin C

Produced with “Ultra-Sonic Molecular Encapsulation” using organic Sunflower Lecithin, Utopia Naturals Liposomal Vitamin C delivers 1000 mg of Vitamin per dose directly to the bloodstream.

The Best Years in Life
P O Box 121 Cooper TX  75432  Phone: 903-886-2436  Fax: 903-829-3434  Email: Dquixote1217[at]gmail.com- (replace [at] with @)

Disclaimer: The information on this page and on this website has not been evaluated by the FDA.  We do not diagnose, treat, cure or prevent illness or disease - instead, we try to help people learn how to do so themselves.  Anyone who believes they have a serious medical condition or health issue should seek diagnoses from a qualified medical professional before making any decisions on how to best address their health. We do not sell or advocate drugs, nor do we make any claims that anything advocated or sold on this website is a drug.  Furthermore, anyone contemplating using any products or information on this website must accept such use as experimental and voluntary.  No claims are made regarding the therapeutic use of the products or information on this website and all products featured or sold on this website must be considered nutritional supplements only.